They’re proposing giving a booster dose of the measles, mumps and rubella (MMR) vaccine to people to see if it ramps up immunity in general, perhaps helping prevent some of the most severe effects of Covid-19.
Their thinking: The MMR vaccine is known to protect kids against infections that go far beyond the three viruses targeted by the vaccine. The theory is that the vaccine boosts general immunity, in addition to training the body to recognize specific viruses.
The MMR vaccine is what’s known as a live vaccine. It uses highly weakened, or attenuated, versions of the measles, mumps and rubella viruses to produce immune protection without making people sick. Because it uses whole viruses, it stimulates an immune response that is broad and goes beyond the production of antibodies.
“A clinical trial with MMR in high-risk populations may provide a ‘low-risk–high-reward’ preventive measure in saving lives during this unprecedented COVID-19 pandemic,” they wrote. There’s no serious risk to giving the vaccine to most people and the approach might be especially effective for protecting health care workers, they said.
“If we’re wrong, well, at least people will have new antibodies to measles, mumps and rubella. So there’s no harm, no foul,” Fidel told CNN.
“We emphasize this is strictly a preventive measure against the worst inﬂammatory sequelae of COVID-19 for those exposed/infected and does not represent an antiviral therapy or vaccine against COVID-19 in any manner,” Fidel and Noverr added in their letter.
Some vaccine experts are dubious about the theory that children are less vulnerable to coronavirus because of recent vaccinations.
Dr. Peter Hotez, a pediatrics professor at the Baylor College of Medicine, said children could be less vulnerable because they have more recently been infected with some of the other coronaviruses that cause the common cold.
“This might stimulate local or systemic cross protecting immunity,” Hotez told CNN.